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KMID : 0816120020050010091
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Korean Journal of Pediatric Gastroenterolology and Nutrition
2002 Volume.5 No. 1 p.91 ~ p.95
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A Case of Eosinophilic Colitis in a 11-year-old Boy
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Nah Joo-Hee
Park Young-Sil
Kim Sun-Mi
Lee Jung-Hyun
Jeong Chang-Mo
Kim Jin-Tack
Chung Seung-Yun
Lee An-Hi
Kang Jin-Han
Lee Joon-Sung
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Abstract
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Eosinophilic gastroenteritis, which shows characteristic eosinophilic inflammation, involves any part of the intestine from esophagus to colon. The immunopathogenesis is expected to be associated with IgE-mediated or non-IgE-mediated reaction, but the precise mechanism is not revealed yet. The clinical manifestation is variably dependent on the extent of eosinophilic infiltration. Usually the symptoms, such as abdominal pain, diarrhea, vomiting, wax and wane for a few months result in failureto thrive, which implicates the importance of early detection. Although the diagnosis is made through clinical and histopathologic evidences, we should suspect the illness in a case of anemia, hypoalbuminemia, and peripheral eosinophilia. Recently, we experienced a case of non- IgE-mediated eosinophilic colitis in a 11-year-old male who complained of diarrhea, right lower abdominal pain, body weight loss, was diagnosed with peculiar histopathologic finding of sigmoid colon specimens obtained by sigmoidoscopy.
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KEYWORD
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Non-IgE-mediated, Eosinophilia
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